“CBD takes the lead cannabis role here as cocaine consumption and anxiety are reduced with repeated CBD treatment. CBD increased expression of cannabinoid receptors, BDNF expression, and neural cell proliferation in the hippocampus, all good things in helping to restructure neural pathways. The evidence for a role of CBD in treating substance abuse continues to point towards potential use in treatment centers.”
- Dr. David Hepburn
Repeated Cannabidiol treatment reduces cocaine intake and modulates neural proliferation and CB1R expression in the mouse hippocampus.
Recent studies on the therapeutic effects of Cannabidiol (CBD) on drug abuse showed mixed results, especially with psychostimulant substances such as cocaine. To determine whether CBD can attenuate cocaine reinforcement, we assessed behavioural responses induced by cocaine in mice, using the behavioural sensitization, conditioned place preference and intravenous self-administration paradigms.
Read full article here:
https://www.ncbi.nlm.nih.gov/pubmed/30273593
Dr. David Hepburn website: https://doctordavidhepburn.com
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