Inflammatory Bowel Responds to THCA

Thursday, 3 January 2019

“With increased interest in the benefits of THCA which, unlike THC, is NON PSYCHOACTIVE, comes this study involving GPR55 receptors in the colon. The evidence of the role of cannabinoids in Crohn’s Disease and Ulcerative Colitis continues to point towards a therapeutic potential of cannabis for these difficult conditions.”
- Dr. David Hepburn


The anti-inflammatory activity of C. Sativa extracts was studied on three lines of epithelial cells and on colon tissue. C. sativa flowers were extracted with ethanol, enzyme-linked immunosorbent assay was used to determine the level of interleukin-8 in colon cells and tissue biopsies, chemical analysis was performed using high-performance liquid chromatography, mass spectrometry and nuclear magnetic resonance and gene expression was determined by quantitative real-time PCR.

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