Two Endocannabinoids Enhance Memory

Tuesday, 22 January 2019

“Both anandamide (AEA) and 2AG play roles in enhancing memory consolidation in the hippocampus. AEA via both CB1 and CB2R while 2AG activates CB2R signaling only.”

- Dr. David Hepburn


The endocannabinoid system is a key modulator of memory consolidation for aversive experiences.
The fatty acid amide hydrolase (FAAH) inhibitor URB597, which increases anandamide levels by inhibiting its hydrolysis, facilitates memory consolidation through a concurrent activation of both cannabinoid receptor type 1 (CB1) and 2 (CB2).

Read the full article here:


Dr. Dave Hepburn website:


Post a Comment

Related Posts Plugin for WordPress, Blogger...