“Add ALS spasticity to MS spasticity as targets for cannabis therapy. A recent Italian study showed those on low dose cannabis spraynotonly improved, but nobody discontinued due to side effects.”
- Dr. David Hepburn
Abstract:
Spasticity is a major determinant of disability and decline in quality of life in patients with motor neuron disease. Cannabinoids have been approved for symptomatic treatment of spasticity in multiple sclerosis. It was investigated whether cannabinoids might also reduce spasticity in patients with motor neuron disease.
Researchers found in this proof-of-concept trial, nabiximols had a positive effect on spasticity symptoms in patients with motor neuron disease and had an acceptable safety and tolerability profile. These findings should be investigated further in larger clinical trials.
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