“As though we need any more reasons to be concerned about the heavy use of cannabis in adolescence, thinning of the brain comes along. Negative effects of chronic adolescent CB use on the hippocampal structure are maintained well into late life. Because hippocampal-cortical loss underlies and exacerbates-related cognitive decline, the findings have profound implications for aging adults with a history of early life usage. A critical brain region the hippocampus (HC), where there is a striking intersection between high concentrations of cannabinoid 1 (CB1) receptors and age-related pathology. They Also Underscores The Persistent Nature of adolescent-induced brain changes due to CB use, and the rising need to understand how these changes interact with brain aging.”
- Dr. David Hepburn
Abstract:
Legalization of cannabis (CB) for both medicinal and, in some states, recreational use, has given rise to increasing usage rates across the country.
Of particular concern are indications that frequent CB use may be selectively harmful to the developing adolescent brain compared with adult-onset usage. However, the long-term effects of heavy, adolescent CB use on brain structure and cognitive performance in late-life remain unknown.
A critical brain region is a hippocampus (HC), where there is a striking intersection between high concentrations of cannabinoid 1 (CB1) receptors and age-related pathology.
Read the full article here:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290479/
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Dr. Dave Hepburn website: https://doctordavidhepburn.com
